Antibiotic Prophylaxis or Pre-Medication

At Christine D. Laster, DDS, we know the human mouth contains a lot of bacteria. A bacterium can travel through your body with routine activities that are a normal part of daily living. You spread bacteria when you brush or floss your teeth, when you chew, and when you swallow.

For most people, bacteria don’t cause any problem. For some people, however, especially those who have chronic medical conditions, specific cardiac conditions, or whose immune systems are compromised, bacteria that spreads throughout the bloodstream can lead to much more serious bacterial infections.

The goal of pre-medication or antibiotic prophylaxis, Dr. Christine D. Laster will tell you, is to prevent bacterial endocarditis, a serious infection of the endothelial heart surfaces or the heart valves. The condition is also called infective endocarditis. A small population of people with certain health problems has a high risk for contracting this potentially deadly bacterium.

The American Heart Association states that people at greatest risk for contracting bacterial or infective endocarditis are:

  • Patients who underwent cardiac valve surgery in the past
  • Those who have suffered past incidents of infective endocarditis
  • Patients who have mitral valve prolapse, resulting in or causing valve leakage
  • People who have had rheumatic fever or any degenerative cardiac condition that produces abnormalities in cardiac valves
  • Patients who suffer from certain congenital heart diseases

For these patients, any dental procedure may cause bleeding, and prophylactic antibiotic administration is recommended as a preventive measure.

Other patients who require prophylactic antibiotics

The American Association of Endodontists extends recommendations to patients who have undergone joint replacement surgery within the past two years, suffer from type 1 diabetes, or have immune deficiencies from diseases such as lupus, rheumatoid arthritis, or HIV; cancer patients whose immune systems are suppressed because of radiation or chemotherapy; people who have had organ transplants; and hemophiliacs.

The American Academy of Pediatric Dentistry also includes people who suffer from sickle cell anemia, as well as patients who suffer from conditions that require chronic steroid therapy.

Typical endodontic procedures for which antibiotic prophylaxis is recommended include root canal therapy (when it involves going deeper than the root apex), surgical tooth extractions, and any other dental, endodontic, or periodontal procedure during which the doctor anticipates bleeding.

Although different medical societies and organizations offer these guidelines as a way of identifying patients for whom prophylactic pre-medication is essential prior to dental procedures, dentists will take each patient’s medical history and personal risk factors into consideration. Some doctors may choose to administer antibiotics following a procedure, especially for patients who have previously suffered from oral infections either as a result of dental procedures or that necessitated oral surgery.

For more information about antibiotic prophylaxis, or to schedule an appointment with Dr. Christine D. Laster, please give us a call at our convenient Raleigh, NC office!

What Our Patients Are Saying

Nathan

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I've been coming to this practice for years now since moving to the Raleigh area. The office is always clean and organized and the staff have always been friendly and communicative. Also, the TV's mounted to the ceiling are a nice touch! I've been seeing Dr. Laster for several years before our insurance changed causing me to change to Dr. Rensch. Both are so easy to talk to and always made me feel at ease.

Jamilah B.

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From beginning to end 5/5! I thought I was experiencing a dental 911. I submitted an inquiry at 11:30pm and by 8am the next morning, Deidra (front office staff) was already leaving me a message. She was so sweet and patient at 8am lol. After our initial conversation, I informed all follow up dentists “I found my dentist office” but thank you so much! Today I was welcomed with the same energy from Diedre to Britany then finally Dr.Wrench. The music playing throughout the office was fantastic; ie music selection and volume. The TV’s on the ceiling and wall made my procedure so painless and enjoyable! I watched an entire Christmas movie lol! Dr. Wrench (apologies for spelling) made my teeth absolutely perfect! I left telling my friends and family I have a million dollar smile! 😊 I can tell he wanted them perfect and he did! Thank you all so much for being amazing! Sincerely, Your next patient.

Rachel F.

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Dr. Laster and Dr. Rensch go above and beyond for their patients. I have seen both for various treatments and I always feel comfortable and heard. They take time to listen and to talk with you. They explain your options and work with you to develop the best plan for your care. They are always upbeat and positive and you can tell they truly love what they do. The front desk staff is exceptional as well. Deidre is so caring and very sweet. She’s efficient, understanding and conscientious of your time. I highly recommend.

Yolanda O.

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Where do I begin?!!! Diedra(front desk) she is an absolute Angel. Her customer service and overall personality was what I truly needed! The Team....OMG they took care of me! Doc made sure I was prepared, comfortable, and overall excited about what was about to happen! I had my procedure 12/20/25 and I can say I feel Great! Still a little swollen but I can see the results and I am very happy!! So if you are on the fence please consider this office because it offers the best experience and the BEST PRICE!!! I CAN'T BELIEVE HOW MUCH I WAS QUOTED AT THE OTHER LOCATION 😖 But anyways, Best Christmas present to myself! Here's to 2026 with a new smile! Come get Yours!😁

Bodie F.

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Connections Dentistry was great! The staff is so friendly and truly cares about their patients. My appointment was quick, and honestly the best dental experience I’ve had. They are great about offering helpful solutions without making you feel like you are being reprimanded… which was the reason I was putting off the dentist. 100% recommend!

Laura P.

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Dr. Rensch and his team are absolutely phenomenal. They are so friendly and enjoyable to work with. It is so convenient to have a Dentist office that also specializes in oral surgery, all in one place! The best in town!

Cala R.

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All the staff is super accommodating and reassuring every step in the process from X-rays, cleaning, treatment plans and scheduling! So grateful I stumbled on other recommendations from patients that led me to my first appointment! Never been so excited to move forward with my future appointments!

Our Patients Stories

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